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What to avoid before and after getting Botox

Learn what to avoid before and after getting Botox with a timeline checklist covering medications, alcohol, exercise, and skincare for best results.

By Dr. Bella Brooks·7 min read·Updated Oct 2026Clinically reviewed
Purely Medspa editorial cover for what to avoid before and after Botox.

You have a Botox appointment on the calendar and want to avoid bruising, migration, and suboptimal results. If you have been searching 'what should I avoid before and after getting Botox,' this checklist covers every substance, medication, and activity to pause, with exact timeframes for when to resume each one.

Pre-treatment avoidance has two goals: minimize bruising and swelling at injection sites, and help the neurotoxin bind to target muscles. The same instructions apply whether you receive Botox, Dysport, Xeomin, Jeuveau, or Daxxify, since all neurotoxins share similar protocols. At Purely Medspa in Boston's Back Bay, each patient gets a written, personalized treatment plan at consultation, so we review these instructions in person before your injection day.

What to avoid before your Botox treatment

Stopping certain medications and supplements before your appointment reduces your risk of bruising. These guidelines apply to all wrinkle relaxer treatments we offer. Here is what to pause and when.

Medications and supplements to discontinue

Five days before your appointment, stop taking aspirin and other NSAIDs, including ibuprofen, Advil, Motrin, Aleve, naproxen, meloxicam, and celecoxib. Stop these blood-thinning supplements at the same time: fish oil, vitamin E, ginkgo biloba, evening primrose oil, St. John's Wort, garlic, and ginseng. Cleveland Clinic recommends avoiding NSAIDs like aspirin, ibuprofen, and naproxen sodium because they raise blood pressure and promote bruising.

If you take prescription blood thinners such as warfarin (Coumadin), heparin, Plavix, or Eliquis, tell your injector before receiving Botox. The FDA-approved Botox labeling advises telling your doctor about all anti-platelet and anti-coagulant medications but does not specify a universal number of days to stop or resume them for cosmetic procedures. The 7-day stop and 2-day resume window referenced in some clinic instructions applies to over-the-counter blood thinners, not prescription anticoagulants. Consult your prescribing physician for individualized guidance. Never stop prescription medications on your own.

The FDA's Botox Cosmetic labeling advises telling your doctor about all prescription and over-the-counter medicines, vitamins, and herbal supplements, because combining Botox with certain other medicines may cause serious side effects. You should also inform your provider if you have received any other botulinum toxin product in the last four months.

What to avoid 24 to 48 hours before Botox

In the 48 hours before your appointment, avoid alcohol. Alcohol dilates blood vessels and increases bruising risk. On the day of treatment, skip caffeine, which can also raise blood pressure and make you more prone to bruising.

Hold off on harsh topical skincare for 24 to 48 hours before your appointment. Retinoids, alpha hydroxy acids (AHAs), and beta hydroxy acids (BHAs) can irritate the skin and make injection sites more sensitive.

What to avoid after your Botox treatment

The neurotoxin is still settling into the targeted muscles right after your injections. What you do in the hours and days afterward affects how well it stays where it was placed.

Immediate avoidances, first few hours

Keep your head upright for at least 3 to 4 hours. Mass General Hospital advises avoiding lying down or strenuous exercise for three hours, and Cleveland Clinic recommends staying upright for three to four hours. Some clinics extend this to 6 hours. Do not do house cleaning, gardening, yoga, or push-ups during this window.

Do not touch, rub, or massage the treated areas. Botox is liquid and can spread, though only by about half an inch. Mass General advises against facials, rubbing, or massaging the treated area for 24 hours.

Skip makeup right after treatment. Injection sites typically close within about 15 minutes, which is the minimum before any product could theoretically be applied. We recommend waiting four to six hours before applying makeup, which gives the sites more time to heal and reduces the risk of pressing the neurotoxin into surrounding muscles.

Mass General suggests exercising your treated muscles for the first hour by frowning, raising your eyebrows, or squinting. This may help, but will not hurt your results if you forget.

First 24 hours after Botox

We recommend waiting 24 hours before resuming strenuous exercise. A higher heart rate sends more blood to the face, which can increase bruising and swelling. Mass General advises a minimum of three hours, but our preferred precaution is the full 24-hour window.

Avoid heat exposure for at least 4 hours after treatment. This includes saunas, hot tubs, tanning beds, and hot showers. Heat raises blood pressure and promotes bruising.

Do not consume alcohol for 48 hours after treatment. Do not get facials, massages, or any cosmetic treatment that applies pressure or heat to the treated areas for 24 hours. Cleveland Clinic suggests waiting longer if you have bruising or swelling, for your own comfort.

Limit sun exposure in the first 24 hours. If unavoidable, use sunscreen with SPF 30 or higher. Avoid hats, headbands, or visors for 24 hours, and skip glasses if the nose was treated.

Small bumps or marks at the injection sites are normal and resolve within a few hours. Apply a cool compress wrapped in a towel for 10 minutes at a time to reduce swelling. For headaches, Tylenol every 4 to 6 hours can help.

Longer-term avoidances, first 1 to 2 weeks

A basic facial that applies only light pressure can be scheduled 24 hours after treatment. More intensive procedures, including chemical peels, microdermabrasion, and laser treatments, require a longer wait of 1 to 2 weeks because they involve deeper pressure or heat on the treated areas. If you are planning additional cosmetic procedures, ask your injector when it is safe to schedule them, since your injector is the final authority on your recovery timeline.

Mass General notes that the weakening effect begins gradually from 3 to 7 days and is not complete for two weeks. Assess your results at the two-week mark, because the effect develops gradually over that period.

Bruising can last up to one week. Arnica gel, oral arnica supplements, and cool compresses applied for 10 to 15 minutes at a time help. You can cover bruising with makeup after the four-to-six-hour waiting period noted above.

Common reactions include redness, swelling, bruising, and tenderness. These usually subside within a few days but can last up to a week. If symptoms persist beyond one week, contact your provider.

When to contact your provider or seek medical attention

Most Botox side effects are mild and temporary. But certain symptoms warrant immediate medical attention.

The FDA's Botox medication guide warns that Botox may cause loss of strength, general muscle weakness, vision problems, or dizziness within hours to weeks of treatment. If this happens, do not drive or operate machinery.

Seek immediate medical attention for difficulty breathing, difficulty swallowing, slurred speech, blurred vision, or signs of an allergic reaction including wheezing, dizziness, or fainting. Cleveland Clinic also lists numbness, paralysis, severe upset stomach, and shortness of breath.

If redness, swelling, or bruising persists beyond one week, or if you develop any new symptoms, contact your injector. At our clinic, the same injector who plans your treatment also performs it, so your provider knows your treatment history and can answer questions specific to your case.

Takeaways

  • Stop aspirin, NSAIDs, fish oil, vitamin E, ginkgo biloba, and St. John's Wort 5 days before treatment
  • Avoid alcohol 48 hours before and after; skip caffeine on treatment day
  • Stay upright for 3 to 4 hours after injections; do not rub or massage for 24 hours
  • Avoid strenuous exercise for 24 hours; avoid saunas, hot tubs, and heat for at least 4 hours
  • Wait 1 to 2 weeks for full results before scheduling facials, peels, or laser treatments

Schedule your Botox consultation in Back Bay

Our clinic uses only FDA-approved products sourced directly from manufacturers. Our zero commission model means your injector recommends only what you need. We do not treat on consultation day unless you request it, so you have time to decide without pressure.

Every patient leaves with a written plan and standardized photography. As a nurse-practitioner led and physician supervised clinic, the same injector plans and performs your treatments.

Book a no-pressure consultation at our Back Bay clinic to build your personalized treatment plan with an injector who will see you through every visit.

Frequently asked

Can I wear makeup to my Botox appointment?
Wait at least four to six hours after your appointment before applying makeup. This gives the injection sites time to close and reduces the risk of pushing the neurotoxin into surrounding muscles. If you need coverage for bruising the next day, apply gently without rubbing.
How long until I see my Botox results?
Most patients see initial softening within three to seven days, with full results visible by the two-week mark. Avoid judging your results until day 14, since the product needs time to fully bind to the targeted muscles.
Is it safe to fly after getting Botox?
Yes, flying is fine after Botox. Cabin pressure does not affect how the neurotoxin settles. Stay hydrated and avoid rubbing your face during the flight. If you had treatment for jaw or clenching issues, ask your injector about any extra precautions.
When can I resume exercise after Botox?
Light walking is fine immediately after treatment. For strenuous exercise, wait 24 hours to give the neurotoxin time to settle and to minimize bruising.
What helps with bruising after Botox?
Bruising is the most common side effect and can last up to a week. See the aftercare section above for the full guidance on arnica gel, cool compresses, and when to apply makeup over bruised areas.
Dr. Bella Brooks
Medical Director & Aesthetic Physician

Dr. Bella Brooks is a medical aesthetics physician at Purely Medspa in Boston, focusing on facial aesthetics, injectables, treatment planning, and natural-looking aesthetic results.

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